Tuesday, June 26, 2012

Vitamin B12 insufficiency

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In comparison to other water-soluble vitamins, vitamin B12 is not excreted in urine, but is stored in the liver, kidney and other body tissues. Hence, it might be five to six years before a someone really develops a insufficiency syndrome for vitamin B12. The general opinion is that body stores do no exhaust before any years.

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How is Vitamin B12 insufficiency

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The coarse symptoms of vitamin B12 deficiencies are inordinate tiredness, breathlessness, listlessness, pallor and poor resistance to infection. insufficiency also can lead to neurological changes such as dullness and tingling in the hands and feet. Other symptoms may contain a reduced sensitivity to pain or pressure, blurred vision, abnormal gait, sore tongue, menstrual disorders and poor concentration levels.

Rather than a dietary deficiency, a insufficiency of vitamin B12 is commonly associated with a malabsorption of it. In such a case, the stomach cannot furnish adequate of a substance called intrinsic factor (If), which is a prerequisite for vitamin B12 absorption. Such a condition, termed pernicious anemia, is an autoimmune dysfunction, wherein the body's immune theory attacks its own tissues. Vegetarians maybe at a risk for facing deficiencies caused by dietary reasons, since the only confirmed source for vitamin B12 intake is the animal source.

Vitamin B12 is indispensable for the formation of red blood cells, and a short furnish of it causes anemia. A insufficiency in Vitamin B12 also results in the disruption of Dna production, and as a result, abnormal cells called megaloblasts occur, foremost to megaloblastic anemia.

Vitamin B12 insufficiency is also associated with any neurological and psychological disorders. A lack of cobalamin results in cognitive decline, nerve degeneration and irreversible neurological damage particularly for adults above fifty. Breast-fed infants of women who effect strict vegetarian diets have very small reserves of this vitamin, and if undetected, vitamin B12 insufficiency in infants can effect in permanent neurological damage. Depression, dementia and Alzheimer's disease are also caused due to a shortage of vitamin B12.

Other effects of insufficiency might be asthma, Aids, multiple sclerosis, tinnitus, diabetic neuropathy and low sperm counts. Ataxia (shaky movements and unsteady gait), muscle weakness, spasticity, incontinence, hypotension, foresight problems, psychoses, and mood disturbances are the other disorders that have recently been associated to possible vitamin B12 deficiencies. Women with breast cancer tend to have lower vitamin B12 levels in their blood serum.

The causes for vitamin B12 insufficiency could be liver damage caused by excess alcohol intake, gastrectomy (i.e. The surgical discharge of part or all of the stomach or discharge of the ileum, a section of the intestine) and a poor functioning of the pancreas. Infection with Helicobacter pylori, a coarse cause of atrophic gastritis and ulcers, can also contribute to adult vitamin B12 deficiency.

Vitamins contain only a tiny part of the food one eats, but a lack of these indispensable micronutrients in one's diet could effect in serious deficiency, which if not cured could endanger one's life.

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